Reshma Kewalramani Ranks Among Fortune’s 2025 100 Most Powerful People

Mumbai-born Reshma Kewalramani, the visionary leader of Vertex Pharmaceuticals, has earned a coveted spot on Fortune’s 2025 100 Most Powerful People in Business, debuting at Ranked #62. Her inclusion highlights an extraordinary journey—from physician to biotech trailblazer—and places her among global icons.
A Trailblazing Indian-Origin Woman CEO
As the Indian-origin woman CEO of a major American biotechnology company, Reshma’s ascent breaks historic ground. At 24, her family moved from Mumbai-born roots to the U.S. at age 11, laying the foundations for a path defined by medicine, innovation, and leadership.
From Physician to Biotech Chief: A Story of Transformation
Her rise from medical doctor to first female CEO of a major U.S. biotech company is a testament to dedication and vision. With clinical roots in top hospitals, Reshma transitioned into biotechnology, joining Vertex and rapidly advancing to Chief Medical Officer before being named CEO in 2020.
Guiding a $110 Billion Biotech Powerhouse
Under her leadership, Vertex Pharmaceuticals—now valued at approximately $110 billion—has solidified its position at the pinnacle of drug discovery. This success story is further accented by FDA approval for Journavx, a groundbreaking non-opioid pain treatment, marking a milestone in the fight against the opioid crisis.
Why Reshma Ranks #62 in Fortune’s Power List
Landing at Ranked #62, Reshma stands shoulder to shoulder with business giants like Zuckerberg, Sundar Pichai, and Mukesh Ambani. Her leadership blends scientific rigor and strategic acumen, all while championing innovation that matters. This recognition signals her growing influence across global business landscapes.
Significance of Her Achievement
This milestone is not just personal—it resonates widely. As an immigrant success story and member of Fortune’s elite list, Reshma’s visibility strengthens representation for women and Indian-origin leaders in STEM and corporate leadership roles. Reshma Kewalramani is more than a CEO—she is a force redefining biotech leadership. Her rise from Mumbai to the top of Vertex Pharmaceuticals, her trailblazing role as the first female CEO in her domain, and her spot on Fortune’s 2025 100 Most Powerful People in Business (at Ranked #62) reinforces how talent, tenacity, and vision can transform industries. Her story inspires—and sets a new standard for aspirational leaders worldwide.